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Antibodies

Anti-Tenascin C Polyclonal Antibody

Product Sizes
100ug
£446.00
OAAI00437-100UG
About this Product
SKU:
OAAI00437
Additional Names:
150-225;cytotactin;deafness; autosomal dominant 56;DFNA56;glioma-associated-extracellular matrix antigen;GMEM;GP;GP 150-225;hexabrachion (tenascin);HXB;JI;myotendinous antigen;neuronectin;tenascin;tenascin-C additional domain 1;TN;TN-C.
Clonality:
Polyclonal
Concentration:
100ug/200ul
Extra Details:
The EWSR1 gene encodes a putative RNA binding protein. Mutation in this gene causes Ewing sarcoma and neuroectodermal and various other tumors. This gene is involved in a number of different sarcomas as a result of chromosomal translocations. EWSR1 is fused to an ETS transcription factor (FLI-1; ERG; ETV-1; E1AF or FEV) in Ewing sarcoma; to activating transcription factor-1 (ATF-1) in soft tissue clear cell sarcoma; to Wilms Tumor -1 (WT1) in desmoplastic small round cell; to nuclear receptor 4A3 (NR4A3) in extraskeletal myxoid chondrosarcoma; and to C/EBP-homologous protein (CHOP) in myxoid liposarcoma. EWSR1 genes are required for mitotic integrity and survival of neural cells in the early embryonic development; and that the involvement of EWSR1 in mitotic stability is conserved from zebrafish to human.
Gene Details:
tenascin C
Host:
Rabbit
Immunogen:
A synthetic peptide corresponding to the internal segment of Tenascin C protein. This sequence is identical among human; rat and mouse.
Isotype:
Rabbit IgG
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody