Anti-Plectin Polyclonal Antibody
Product Sizes
100ug
£435.00
OAAI00436-100UG
About this Product
- SKU:
- OAAI00436
- Additional Names:
- EBS1;EBSMD;EBSND;EBSO;EBSOG;EBSPA;HD1;hemidesmosomal protein 1;LGMD2Q;LGMDR17;PCN;PLEC1;PLEC1b;plectin;plectin 1; intermediate filament binding protein 500kDa;PLTN.
- Clonality:
- Polyclonal
- Concentration:
- 100ug/200ul
- Extra Details:
- Plectin is a cytoskeleton linker protein expressed in a variety of tissues including skin; muscle; and nerves. Plectin can bind to several molecules (intermediate filaments) that make up the cytoskeleton. Mutations in its gene are associated with epidermolysis bullosa simplex with late-onset muscular dystrophy. In certain skin cells; this protein is an essential part of hemidesmosomes; which attach the network of intermediate filaments to the cell membrane. It is also a component of desmosomes; which form junctions between neighboring cells. As part of these structures; plectin plays a critical role in anchoring the outer layer of the skin (the epidermis) to underlying layers. Mutations in the PLEC1 gene also cause at least two other forms of epidermolysis bullosa
- Gene Details:
- plectin
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to the C-term portion of human Plectin. This sequence is identical to rat; mouse and human origins.
- Isotype:
- Rabbit IgG
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
