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Antibodies

Anti-P53 Antibody

Product Sizes
100ug
£424.00
OAAI00414-100UG
About this Product
SKU:
OAAI00414
Additional Names:
antigen NY-CO-13;BCC7;BMFS5;cellular tumor antigen p53;LFS1;mutant tumor protein 53;P53;p53 tumor suppressor;phosphoprotein p53;transformation-related protein 53;TRP53;tumor protein 53;tumor supressor p53.
Clonality:
Polyclonal
Concentration:
100ug/200ul
Extra Details:
P53; also known as protein 53; or tumor suppressor protein 53; plays important roles in cellular response to DNA damage and other genomic aberRation. Mutations in the p53 tumor suppressor gene giving rise to mutant p53 proteins are among the most common genetic alteRations associated with tumor cells. P53 protein is phosphrylated at multiple sites in vivo and in vitro in response to different stimuli. UV caused DNA damage can induce Ser9; Ser15; Ser20 phosphorylation while ATM; ATR; DNA-PK at Ser15 and Ser37.
Gene Details:
tumor protein p53
Host:
Rabbit
Immunogen:
A synthetic peptide corresponding to the epitope -PLSQE- at a phosphorylation site at serine 15 of human p53 protein
Isotype:
Rabbit IgG
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody