Anti-Saposin Antibody
Product Sizes
100ug
£424.00
OAAI00406-100UG
About this Product
- SKU:
- OAAI00406
- Additional Names:
- GLBA;PARK24;proactivator polypeptide;prosaposin;PSAPD;SAP1;SAP2;saposin-A;saposin-B;saposin-C;saposin-D;sphingolipid activator protein-1;sphingolipid activator protein-2.
- Clonality:
- Polyclonal
- Concentration:
- Varies by lot. See vial for concentration.
- Extra Details:
- The Saposin family includes four structurally related proteins; saposin A; B; C; and D which are ~80 aa small acidic acitvator proteins with specificities for glycosphingolipid (GSL) hydrolases. They are derived from a single precursor; prosaposin.
In both Humans and mice; prosaposin/saposin deficiencies lead to severe neurological deficits. Saposins are processed from prosaposin in the late endosome and lysosome; and their stability is maintained by three disulfide bridges. The post-modified prosoposin is an ~70 kDa form which subsequently undergoes partial proteolysis to produce saposin A; B; C; and D; each proteins are between 12-14 kDa in mass. - Gene Details:
- prosaposin
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to internal sequence (within 300-360aa) of human Saposin.
- Isotype:
- Rabbit IgG
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- The antibodies are stable for 24 months from date of receipt when stored at -20°C to -70°C. The antibodies can be stored at 2-8°C for three months without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
