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Antibodies

Anti-Rat HSF2 Monoclonal Antibody

Product Sizes
100ug
£489.00
OAAI00311-100UG
About this Product
SKU:
OAAI00311
Additional Names:
heat shock factor protein 2;HSF 2;HSTF 2.
translate.label.attr.clone:
ABM402
Clonality:
Monoclonal
Concentration:
100ug/200ul
Extra Details:
Heat-shock factors(HSF1-4) play important roles in responding to the cellular stress signals; such as heat; heavy metals; and oxidative reagents and a wide variety of other stressors. HSF1 is activated by stress; whereas HSF2 lacks intrinsic stress responsiveness althoμgh the HSF2 expression changes which is coinciding with the functions of HSF2 in development. HSF1 and HSF2 form heterotrimers when bound to satellite III DNA in nuclear stress bodies; subnuclear structures in which HSF1 induces transcription. Upon stress; HSF2 DNA binding is HSF1 dependent. The heterotrimerization of HSF1 and HSF2 integRates transcriptional activation in response to distinct stress and developmental stimuli.
Gene Details:
heat shock transcription factor 2
Host:
Rat
Immunogen:
A recombinant human HSF2 (1-536aa) protein
Isotype:
Rat IgG1
Purification:
The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
Shipping Conditions:
Blue Ice
Storage Conditions:
The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody