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Antibodies

Anti-PSAP Monoclonal Antibody

Product Sizes
100ug
£413.00
OAAI00278-100UG
About this Product
SKU:
OAAI00278
Additional Names:
GLBA;PARK24;proactivator polypeptide;prosaposin;PSAPD;SAP1;SAP2;saposin-A;saposin-B;saposin-C;saposin-D;sphingolipid activator protein-1;sphingolipid activator protein-2.
translate.label.attr.clone:
ABM312
Clonality:
Monoclonal
Concentration:
100ug/200ul
Extra Details:
Prostate specific acid phosphatase (PSAP) is a 100 kD glycoprotein present in high concentRation in the prostate gland and its secretions. It is one of the two antigenic markers of prostatic carcinoma; the other being prostate specific antigen. It belongs to the kallikrein family of serine proteases and is sμggested to act as a hydrolase to split phospharyl choline in semen and as a transferase. PSAP is measured clinically because its level often rises in the serum in cases of prostatic carcinoma. By immunohistochemical analysis PSAP has been found concentRated within the large secretory vacuoles of the supranuclear portion of the prostatic columnar epithelial cell. In hyperplastic prostates and in benign prostatic tissue adjacent to the prostatic carcinoma; PSAP activity is limited to the acinar or ductal columnar epithelial cells and adjacent luminal content. PSAP reactivity in an extraprostatic tumor is an accuRate and sensitive indicator of metastatic prostatic carcinoma.
Gene Details:
prosaposin
Host:
Mouse
Immunogen:
Partially purified prostate acid phosphatase from human seminal plasma.
Isotype:
IgG1
Purification:
The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
Shipping Conditions:
Blue Ice
Storage Conditions:
The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody