Anti-eNOS Antibody
Product Sizes
100ug
£532.00
OAAI00234-100UG
About this Product
- SKU:
- OAAI00234
- Additional Names:
- cNOS;constitutive NOS;ECNOS;EC-NOS;endothelial NOS;eNOS;nitric oxide synthase 3 (endothelial cell);nitric oxide synthase 3 transcript variant eNOS-delta20;nitric oxide synthase 3 transcript variant eNOS-delta20-21;nitric oxide synthase 3 transcript variant eNOS-delta21;nitric oxide synthase; endothelial;NOS type III;NOSIII.
- Clonality:
- Polyclonal
- Concentration:
- 100ug/200ul
- Extra Details:
- NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. Nitric oxide (NO) is an inorganic; gaseous free radical that carries a variety of messages between cells. Vasorelaxation; neurotransmission and cytotoxicity can all be enhanced throμgh cellular response to NO. NO production is mediated by members of the nitric oxide synthase (NOS) family. There are three types of NOS: two constitutive isoforms; brain or neuronal NOS (b or nNOS; type I) & endothelial cell NOS (eNOS; type III); and one inducible isoform (iNOS; type II). iNOS is found in a variety of cell types including macrophages; hepatocytes; synoviocytes; and smooth muscle cells. Cytokines such as interferon-gamma (IFN); tumor necrosis factor (TNF); interleukin-1 and -2; and lipopolysaccarides (LPS) cause an increase in iNOS mRNA; protein; and activity levels. The phosphorylation of eNOS by Protein kinase C was associated with an increase in NO production.
- Gene Details:
- nitric oxide synthase 3
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to the internal sequence (residing in 550-650aa) of human eNOS protein.
- Isotype:
- Rabbit IgG
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
