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Antibodies

Anti-GluR6/7 Polyclonal Antibody

Product Sizes
100ug
£511.00
OAAI00175-100UG
About this Product
SKU:
OAAI00175
Additional Names:
bA487F5.1;EAA4;excitatory amino acid receptor 4;GLR6;GluK2;GluK2(alt_5'UTR);GLUK6;gluR-6;GLUR6;glutamate receptor 6;glutamate receptor form A;glutamate receptor form B;glutamate receptor form C;glutamate receptor form D;glutamate receptor form E;glutamate receptor ionotropic; kainate 2;MRT6;putative NMDtranscript(cassette_171nt).
Clonality:
Polyclonal
Concentration:
100ug/200ul
Extra Details:
Glutamate receptors (GluR) are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Two classes of glutamate receptors exist: ionotropic receptors; and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR1-7; NMDA1- 3; KAI-2); which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors. GluR6 belongs to the kainate family of glutamate receptors; which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains; which is thoμght to alter the structure and function of the receptor complex.
Mutations in this gene have been associated with autosomal recessive mental retardation.
Gene Details:
glutamate ionotropic receptor kainate type subunit 2
Host:
Rabbit
Immunogen:
A synthetic peptide derived from C-terminus of Glutamate receptor 6/7 Protein. This sequence is identical to human; mouse and rat.
Isotype:
Rabbit IgG
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody