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Antibodies

Anti-Caspase-9 Polyclonal Antibody

Product Sizes
100ug
£619.00
OAAI00148-100UG
About this Product
SKU:
OAAI00148
Additional Names:
APAF3;APAF-3;apoptotic protease activating factor 3;apoptotic protease MCH-6;caspase 9; apoptosis-related cysteine peptidase;caspase-9;ICE-LAP6;ICE-like apoptotic protease 6;MCH6;PPP1R56;protein phosphatase 1; regulatory subunit 56.
Clonality:
Polyclonal
Concentration:
100ug/200ul
Extra Details:
Caspase-9 belongs to a member of the cysteine-aspartic acid protease (Caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits; large and small. Those dimerize to form the active enzyme. Activation of procaspase-9 by Apaf-1 in the Cytochrome C/dATP-dependent pathway requires proteolytic cleavage to geneRate the mature caspase molecule. Once activated; caspase-9 can initiate a caspase cascade involving the downstream executioner caspase-3; -6 and -7.
Gene Details:
caspase 9
Host:
Rabbit
Immunogen:
A synthetic peptide derived from N-terminus of human Caspase 9 protein.
Isotype:
Rabbit IgG
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody