Anti-Estrogen Receptor 1 Polyclonal Antibody
Product Sizes
100ug
£532.00
OAAI00127-100UG
About this Product
- SKU:
- OAAI00127
- Additional Names:
- E2 receptor alpha;ER;Era;ER-alpha;ESR;ESRA;estradiol receptor;estrogen nuclear receptor alpha;estrogen receptor;estrogen receptor alpha E1-E2-1-2;estrogen receptor alpha E1-N2-E2-1-2;ESTRR;NR3A1;nuclear receptor subfamily 3 group A member 1;oestrogen receptor alpha.
- Clonality:
- Polyclonal
- Concentration:
- 100ug/200ul
- Extra Details:
- ER (estrogen receptor) belongs to a member of the steroid receptor superfamily; a ligand-activated transcription factor composed of several domains important for hormone binding; DNA binding and activation of transcription. This protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function; but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer; endometrial cancer; and osteoporosis. ER regulates transcription by its phosphorylation at multiple sites; such as serine 104; 106; 118; 167 and 305.
Phosphorylation of certain serine at ER may relate to breast cancer process and on-going treatment. - Gene Details:
- estrogen receptor 1
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to the C-terminus of human estrogen receptor protein. This sequence is identical to human; Gorilla; Bovine; etc.
- Isotype:
- Rabbit IgG
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
