Anti-E2F2 Polyclonal Antibody
Product Sizes
100ug
£467.00
OAAI00116-100UG
About this Product
- SKU:
- OAAI00116
- Additional Names:
- E2F-2;transcription factor E2F2.
- Clonality:
- Polyclonal
- Concentration:
- 100ug/200ul
- Extra Details:
- E2F2 belongs to E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins; and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain; a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP); a transactivation domain enriched in acidic amino acids; and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members; E2F1 and E2F3; have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner; and it exhibits overall 46% amino acid identity to E2F1.
- Gene Details:
- E2F transcription factor 2
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to N-terminal of human E2F2.
- Isotype:
- Rabbit IgG
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
