Anti-Sentrin-2/SUMO-2 Polyclonal Antibody
Product Sizes
100ug
£457.00
OAAI00015-100UG
About this Product
- SKU:
- OAAI00015
- Additional Names:
- HSMT3;sentrin 2;small ubiquitin-related modifier 2;SMT3 homolog 2;SMT3 suppressor of mif two 3 homolog 2;Smt3A;SMT3B;SMT3H2;SUMO3;ubiquitin-like protein SMT3A;ubiquitin-like protein SMT3B.
- Clonality:
- Polyclonal
- Concentration:
- 100ug/200ul
- Extra Details:
- Sentrin-2 also known as SUMO-2 is a 95-amino acids peptide that has high homologous to Sentrin-1/SUMO-1. This novel ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer.
Covalent attachment via an isopeptide bond to its substRates requires prior activation by the E1 complex SAE1-SAE2 and linage to the E2 enzyme UBE2I; and can be promoted by an E3 ligase such as PIAS1-4; RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport; DNA replication and repair; mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. - Gene Details:
- small ubiquitin like modifier 2
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide derived from C-terminus of human Sentrin-2 protein. This sequence is identical to human; mouse and rat.
- Isotype:
- Rabbit IgG
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
