Anti-SOCS-5 Polyclonal Antibody
Product Sizes
100ug
£424.00
OAAI00007-100UG
About this Product
- SKU:
- OAAI00007
- Additional Names:
- CIS6;CIS-6;Cish5;CISH6;cytokine-inducible SH2 protein 6;cytokine-inducible SH2-containing protein 5;SOCS-5;suppressor of cytokine signaling 5.
- Clonality:
- Polyclonal
- Concentration:
- 100ug/200ul
- Extra Details:
- Cytokines induce a variety of biological responses by binding to specific cell surface receptors and activating cytoplasmic signal transduction pathways which are suppressed by other transcriptional factors. Proteins that mediate these signals from the cell surface to the nucleus include JAKs and STATs; while SOCS (Suppressor of cytokine signaling) proteins inhibit those signaling. The SOCS family comprises at least 8 members; SOCS1 to SOCS7 and CIS (cytokine inducible SH2 containing protein). Structurally; the SOCS proteins are composed of an N terminal region of variable length and amino acid composition; a central SH2 domain; and a previously unrecognized C terminal motif named the SOCS box. SOCS5 regulates IL-4 signaling throμgh JAK1 negatively.
- Gene Details:
- suppressor of cytokine signaling 5
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to the C-terminus of SOCS-5 protein from human; mouse and rat origins
- Isotype:
- Rabbit IgG
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
