B-Catenin Antibody
Product Sizes
100 ul
£370.00
OAAH00021-100UL
About this Product
- SKU:
- OAAH00021
- Additional Names:
- EVR7; CTNNB; MRD19; NEDSDV; armadillo
- translate.label.attr.clone:
- 44C6
- Clonality:
- Monoclonal
- Extra Details:
- The catenins; a ; B and; are proteins which bind to the highly conserved; intracellular cytoplasmic tail of E-cadherin. Together; the catenin/cadherin complexes play an important role mediating cellular adhesion. -catenin was initially described as an E-cadherin associated protein; and since has been shown to associate with other members of the cadherin family; such as Ncadherin and P-cadherin. -catenin associates with the cytoplasmic portion of E-cadherin; which is necessary for the function of E-cadherin as an adhesion molecule. -catenin has also been found in complexes with the tumor suppressor protein APC. -catenin; also known as plakoglobin; is a protein that binds with -catenin and N-cadherin. It has been shown that the transmembrane phosphatase PTP associates with catenin/cadherin complexes and may regulate complex signaling.
- Host:
- Mouse
- Immunogen:
- This Aviva monoclonal antibody is produced by immunizing mice with a synthetic peptide (KLH-coupled) corresponding to carboxy-terminal residues of human Beta-catenin.
- Isotype:
- Mouse IgG1
- Molecular Weight:
- 85 kDa
- Protein Details:
- Catenin beta-1
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C after receipt. Stable for one year from the date of shipment.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
