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Antibodies

S100B Antibody

Product Sizes
50ul
£359.00
OAAF08347-50UL
100ul
£496.00
OAAF08347-100UL
About this Product
SKU:
OAAF08347
Additional Names:
NEF; S100; S100-B; S100beta
translate.label.attr.clone:
ABT-S100B
Clonality:
Monoclonal
Extra Details:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells; and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however; this gene is located at 21q22.3. This protein may function in Neurite extension; proliferation of melanoma cells; stimulation of Ca2+ fluxes; inhibition of PKC-mediated phosphorylation; astrocytosis and axonal proliferation; and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological; neoplastic; and other types of diseases; including Alzheimer's disease; Down's syndrome; epilepsy; amyotrophic lateral sclerosis; melanoma; and type I diabetes.
Gene Details:
S100 calcium binding protein B
Host:
Mouse
Immunogen:
The antiserum was produced against synthesized peptide derived between 10-50 aa of human S100B. The exact sequence is proprietary.
Isotype:
IgG
Molecular Weight:
11 kDa
Protein Details:
protein S100-B
Purification:
Immunogen affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
Shipped at 4C. Store at -20C. Stable for 12 months at -20C.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody