IL28A Antibody
Product Sizes
100 ug
£496.00
OAAF08163-100UG
About this Product
- SKU:
- OAAF08163
- Additional Names:
- cytokine Zcyto20;IFNL2a;IFNL3a;IFN-lambda-2;IL28A;IL-28A;interferon lambda-2;interleukin 28A (interferon; lambda 2);interleukin-28A.
- Clonality:
- Polyclonal
- Concentration:
- 1mg/ml
- Extra Details:
- Cytokine with antiviral; antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense; predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1; and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG); which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection; but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
- Gene Details:
- interferon lambda 2
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from the C-terminal region of human IL28A.
- Molecular Weight:
- 22 kda
- Protein Details:
- Interferon lambda-2
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using peptide.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
