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Antibodies

IL29 Antibody

Product Sizes
100 ug
£496.00
OAAF08157-100UG
About this Product
SKU:
OAAF08157
Additional Names:
cytokine Zcyto21;IFN-lambda-1;IL29;IL-29;interferon lambda-1;interleukin 29 (interferon; lambda 1);interleukin-29.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Cytokine with antiviral; antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense; predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1; and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG); which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Gene Details:
interferon lambda 1
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from the Internal region of human IL29.
Molecular Weight:
21 kDa
Protein Details:
Interferon lambda-1
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using peptide.
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody