PTPRJ Antibody
Product Sizes
100 ug
£496.00
OAAF08122-100UG
About this Product
- SKU:
- OAAF08122
- Additional Names:
- CD148;CD148 antigen;density-enhanced phosphatase 1;DEP1;DEP-1;HPTP eta;HPTPeta;human density enhanced phosphatase-1;protein tyrosine phosphatase; receptor type; J polypeptide;protein-tyrosine phosphatase eta;Protein-tyrosine phosphatase receptor type J;receptor-type tyrosine-protein phosphatase eta;R-PTP-ETA;R-PTP-J;SCC1;susceptibility to colon cancer 1; mouse; homolog of.
- Clonality:
- Polyclonal
- Concentration:
- 1mg/ml
- Extra Details:
- Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1; FLT3; PDGFRB; MET; RET (variant MEN2A); KDR; LYN; SRC; MAPK1; MAPK3; EGFR; TJP1; OCLN; PIK3R1 and PIK3R2. Plays a role in cell adhesion; migration; proliferation and differentiation. Involved in vascular development. Regulator of macrophage adhesion and spreading. Positively affects cell-matrix adhesion. Positive regulator of platelet activation and thrombosis. Negative regulator of cell proliferation. Negative regulator of PDGF-stimulated cell migration; through dephosphorylation of PDGFR. Positive regulator of endothelial cell survival; as well as of VEGF-induced SRC and AKT activation; through KDR dephosphorylation. Negative regulator of EGFR signaling pathway; through EGFR dephosphorylation. Enhances the barrier function of epithelial junctions during reassembly. Negatively regulates T-cell receptor (TCR) signaling. Upon T-cell TCR activation; it is up-regulated and excluded from the immunological synapses; while upon T-cell-antigen presenting cells (APC) disengagement; it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling.
- Gene Details:
- protein tyrosine phosphatase receptor type J
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from the Internal region of human PTPRJ.
- Molecular Weight:
- 145 kDa
- Protein Details:
- Receptor-type tyrosine-protein phosphatase eta
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using peptide.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
