PVRL3 Antibody
Product Sizes
100 ug
£496.00
OAAF08108-100UG
About this Product
- SKU:
- OAAF08108
- Additional Names:
- CD113;CDW113;nectin 3;Nectin cell adhesion molecule 3;nectin-3;poliovirus receptor-related 3;poliovirus receptor-related protein 3;PPR3;PRR3;PVRL3;PVRR3.
- Clonality:
- Polyclonal
- Concentration:
- 1mg/ml
- Extra Details:
- Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins; such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions; including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface; resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
- Gene Details:
- nectin cell adhesion molecule 3
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from the Internal region of human PVRL3.
- Molecular Weight:
- 61 kDa
- Protein Details:
- Nectin-3
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using peptide.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
