WTAP Antibody
Product Sizes
100 ug
£496.00
OAAF07909-100UG
About this Product
- SKU:
- OAAF07909
- Additional Names:
- female-lethal(2)D homolog;hFL(2)D;Mum2;PNAS-132;pre-mRNA-splicing regulator WTAP;putative pre-mRNA splicing regulator female-lethal(2D);Wilms tumor 1 associated protein;wilms tumor 1-associating protein;Wilms' tumour 1-associating protein;WT1-associated protein.
- Clonality:
- Polyclonal
- Concentration:
- 1mg/ml
- Extra Details:
- Associated component of the WMM complex; a complex that mediates N6-methyladenosine (m6A) methylation of RNAs; a modification that plays a role in the efficiency of mRNA splicing and RNA processing (PubMed:29507755). Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed:24316715; PubMed:24407421; PubMed:24981863). Acts as a mRNA splicing regulator (PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2; which enhances its stability (PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed:17095724).
- Gene Details:
- WT1 associated protein
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human WTAP.
- Molecular Weight:
- 44 kDa
- Protein Details:
- Pre-mRNA-splicing regulator WTAP
- Purification:
- The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
