XRCC2 Antibody
Product Sizes
100 ug
£496.00
OAAF07901-100UG
About this Product
- SKU:
- OAAF07901
- Additional Names:
- DNA repair protein XRCC2;epididymis secretory sperm binding protein;FANCU;POF17;SPGF50;X-ray repair complementing defective repair in Chinese hamster cells 2;X-ray repair cross-complementing protein 2.
- Clonality:
- Polyclonal
- Concentration:
- 1mg/ml
- Extra Details:
- Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA; thought to repair chromosomal fragmentation; translocations and deletions. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage; BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA; single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
- Gene Details:
- X-ray repair cross complementing 2
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human XRCC2.
- Molecular Weight:
- 31 kDa
- Protein Details:
- DNA repair protein XRCC2
- Purification:
- The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
