NIPA Antibody
Product Sizes
100 ug
£496.00
OAAF07639-100UG
About this Product
- SKU:
- OAAF07639
- Additional Names:
- hematopoietic stem/progenitor cell protein 216;HSPC216;NIPA;nuclear interacting partner of anaplastic lymphoma kinase (ALK);nuclear-interacting partner of ALK;Nuclear-interacting partner of anaplastic lymphoma kinase;Zinc finger C3HC-type protein 1.
- Clonality:
- Polyclonal
- Concentration:
- 1mg/ml
- Extra Details:
- Essential component of a SCF-type E3 ligase complex; SCF(NIPA); a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex; restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.
- Gene Details:
- zinc finger C3HC-type containing 1
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human NIPA around the phosphorylation site of Ser354.
- Molecular Weight:
- 55 kDa
- Protein Details:
- Nuclear-interacting partner of ALK
- Purification:
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
