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Antibodies

HER3 Antibody

Product Sizes
100 ug
£496.00
OAAF07573-100UG
About this Product
SKU:
OAAF07573
Additional Names:
c-erbB3;c-erbB-3;ErbB-3;erbB3-S;FERLK;HER3;human epidermal growth factor receptor 3;LCCS2;MDA-BF-1;p180-ErbB3;p45-sErbB3;p85-sErbB3;proto-oncogene-like protein c-ErbB-3;receptor tyrosine-protein kinase erbB-3;tyrosine kinase-type cell surface receptor HER3;v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3;VSCN1.
Clonality:
Polyclonal
Concentration:
1mg/ml
Extra Details:
Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). May also be activated by CSPG5 (PubMed:15358134).
Gene Details:
erb-b2 receptor tyrosine kinase 3
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human HER3 around the phosphorylation site of Tyr1289.
Molecular Weight:
148 kDa
Protein Details:
Receptor tyrosine-protein kinase erbB-3
Purification:
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody