AMPK beta1 Antibody
Product Sizes
100 ug
£496.00
OAAF07344-100UG
About this Product
- SKU:
- OAAF07344
- Additional Names:
- 5'-AMP-activated protein kinase beta-1 subunit;5'-AMP-activated protein kinase subunit beta-1;AMP-activated protein kinase beta subunit;AMPK;AMPK beta 1;AMPK beta -1 chain;AMPK subunit beta-1;AMPKb;HAMPKb;protein kinase; AMP-activated; beta 1 non-catalytic subunit;protein kinase; AMP-activated; noncatalytic; beta-1.
- Clonality:
- Polyclonal
- Concentration:
- 1mg/ml
- Extra Details:
- Non-catalytic subunit of AMP-activated protein kinase (AMPK); an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels; AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein; carbohydrate and lipid biosynthesis; as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes; and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles; via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1; PRKAG2 or PRKAG3).
- Gene Details:
- protein kinase AMP-activated non-catalytic subunit beta 1
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human AMPK beta1 around the phosphorylation site of Ser181.
- Molecular Weight:
- 30 kDa
- Protein Details:
- 5'-AMP-activated protein kinase subunit beta-1
- Purification:
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
