CASP3
Product Sizes
100 ug
£496.00
OAAF05314-100UG
About this Product
- SKU:
- OAAF05314
- Additional Names:
- apopain;CASP-3;caspase 3; apoptosis-related cysteine peptidase;caspase 3; apoptosis-related cysteine protease;caspase-3;CPP32;CPP-32;CPP32B;cysteine protease CPP32;PARP cleavage protease;procaspase3;protein Yama;SCA-1;SREBP cleavage activity 1.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6; -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
- Gene Details:
- caspase 3
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Caspase 3.
- Isotype:
- IgG
- Molecular Weight:
- 20 kDa
- Protein Details:
- Caspase-3
- Purification:
- The antibody was purified from rabbit antiserum by affinity chromatography using immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
