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Antibodies

LGR6 Antibody

Product Sizes
100 ug
£496.00
OAAF04975-100UG
About this Product
SKU:
OAAF04975
Additional Names:
gonadotropin receptor;GPCR;leucine-rich repeat-containing G-protein coupled receptor 6;VTS20631.
Clonality:
Polyclonal
Extra Details:
Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1; RSPO2; RSPO3 or RSPO4); associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors; triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors; does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
Gene Details:
leucine rich repeat containing G protein-coupled receptor 6
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human LGR6.
Molecular Weight:
104 kDa
Protein Details:
Leucine-rich repeat-containing G-protein coupled receptor 6
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody