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Antibodies

GCGR Antibody

Product Sizes
100 ug
£496.00
OAAF04902-100UG
About this Product
SKU:
OAAF04902
Additional Names:
GGR;GL-R;glucagon receptor;MVAH.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors; such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides; plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
Gene Details:
glucagon receptor
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human GLR.
Isotype:
IgG
Molecular Weight:
54 kDa
Protein Details:
Glucagon receptor
Purification:
The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody