APLNR Antibody
Product Sizes
100 ug
£496.00
OAAF04771-100UG
About this Product
- SKU:
- OAAF04771
- Additional Names:
- AGTRL1;angiotensin II receptor-like 1;angiotensin receptor-like 1;apelin receptor;APJ;APJ (apelin) receptor;APJ receptor;APJR;G protein-coupled receptor APJ;G-protein coupled receptor APJ;G-protein coupled receptor HG11;HG11;HG11 orphan receptor.
- Clonality:
- Polyclonal
- Extra Details:
- Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity (PubMed:11090199; PubMed:25639753; PubMed:28137936). Plays a key role in early development such as gastrulation; blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone (By similarity). May promote angioblast migration toward the embryonic midline; i.e. the position of the future vessel formation; during vasculogenesis (By similarity). Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development (By similarity). Plays also a role in various processes in adults such as regulation of blood vessel formation; blood pressure; heart contractility and heart failure (PubMed:25639753; PubMed:28137936).
- Gene Details:
- apelin receptor
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human AGTRL1.
- Molecular Weight:
- 42 kDa
- Protein Details:
- Apelin receptor
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
