ARHGEF5 Antibody
Product Sizes
100 ug
£496.00
OAAF04193-100UG
About this Product
- SKU:
- OAAF04193
- Additional Names:
- ephexin3;ephexin-3;GEF5;guanine nucleotide regulatory protein TIM;oncogene TIM;P60;p60 TIM;Rho guanine nucleotide exchange factor (GEF) 5;rho guanine nucleotide exchange factor 5;TIM;TIM1;transforming immortalized mammary oncogene.
- Clonality:
- Polyclonal
- Extra Details:
- Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:15601624). Strongly activates RHOA (PubMed:15601624). Also strongly activates RHOB; weakly activates RHOC and RHOG and shows no effect on RHOD; RHOV; RHOQ or RAC1 (By similarity). Involved in regulation of cell shape and actin cytoskeletal organization (PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (PubMed:14662653). Required for SRC-induced podosome formation (By similarity). Involved in positive regulation of immature dendritic cell migration (By similarity).
- Gene Details:
- Rho guanine nucleotide exchange factor 5
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human ARHGEF5.
- Molecular Weight:
- 60 kDa
- Protein Details:
- Rho guanine nucleotide exchange factor 5
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
