ARHGAP17 Antibody
Product Sizes
100 ug
£496.00
OAAF04182-100UG
About this Product
- SKU:
- OAAF04182
- Additional Names:
- MST066;MST110;MSTP038;MSTP066;MSTP110;NADRIN;neuron-associated developmentally regulated protein;PP367;PP4534;rho GTPase-activating protein 17;RhoGAP interacting with CIP4 homologs 1;RhoGAP interacting with CIP4 homologs protein 1;rho-type GTPase-activating protein 17;RICH1;RICH-1;WBP15.
- Clonality:
- Polyclonal
- Extra Details:
- Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42; thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions; possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca(2+)-dependent regulation of exocytosis; possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.
- Gene Details:
- Rho GTPase activating protein 17
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human RHG17.
- Molecular Weight:
- 95 kDa
- Protein Details:
- Rho GTPase-activating protein 17
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
