MOV10L1 Antibody
Product Sizes
100 ug
£496.00
OAAF04097-100UG
About this Product
- SKU:
- OAAF04097
- Additional Names:
- cardiac helicase activated by MEF2C protein;CHAMP;DJ402G11.8;moloney leukemia virus 10-like protein 1;Mov10 RISC complex RNA helicase like 1;Mov10l1; Moloney leukemia virus 10-like 1; homolog;Mov10-like 1;MOV10-like protein 1;putative helicase Mov10l1;RNA helicase Mov10l1.
- Clonality:
- Polyclonal
- Extra Details:
- ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization; which is essential for germline integrity. Acts via the piRNA metabolic process; which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the primary piRNA metabolic process. Specifically binds to piRNA precursors and promotes the generation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins. Acts via its ATP-dependent RNA helicase activity: displays 5'-3' RNA unwinding activity and probably mediates unwinding and funneling of single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins.
- Gene Details:
- Mov10 like RISC complex RNA helicase 1
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human MOV10L1.
- Molecular Weight:
- 135 kDa
- Protein Details:
- RNA helicase Mov10l1
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
