SF3B14 Antibody
Product Sizes
100 ug
£496.00
OAAF04050-100UG
About this Product
- SKU:
- OAAF04050
- Additional Names:
- CGI-110;HSPC175;Ht006;P14;pre-mRNA branch site protein p14;SAP14;SAP14a;SF3b 14 kDa subunit;SF3B14;SF3B14a;spliceosome-associated protein; 14 kDa subunit;spliceosome-associated protein; 14-kDa;splicing factor 3B subunit 6;splicing factor 3B; 14 kDa subunit;splicing factor 3b; subunit 6; 14kDa.
- Clonality:
- Polyclonal
- Extra Details:
- Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA (PubMed:12234937). Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing (PubMed:16432215). Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or; in the case of the minor spliceosome; as part of the 18S U11/U12 snRNP complex; and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively (PubMed:16432215).
- Gene Details:
- splicing factor 3b subunit 6
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human SF3B14.
- Molecular Weight:
- 14 kDa
- Protein Details:
- Splicing factor 3B subunit 6
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
