POLR3E Antibody
Product Sizes
100 ug
£496.00
OAAF03591-100UG
About this Product
- SKU:
- OAAF03591
- Additional Names:
- C37;DNA-directed RNA polymerase III 80 kDa polypeptide;DNA-directed RNA polymerase III subunit RPC5;polymerase (RNA) III (DNA directed) polypeptide E (80kD);polymerase (RNA) III subunit E;RNA polymerase III 80 kDa subunit RPC5;RNA polymerase III subunit C5;RPC5;SIN.
- Clonality:
- Polyclonal
- Extra Details:
- DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs; such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts; such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
- Gene Details:
- RNA polymerase III subunit E
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human RPC5.
- Molecular Weight:
- 79 kDa
- Protein Details:
- DNA-directed RNA polymerase III subunit RPC5
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
