ATG4A Antibody
Product Sizes
100 ug
£496.00
OAAF03545-100UG
About this Product
- SKU:
- OAAF03545
- Additional Names:
- APG4 autophagy 4 homolog A;APG4A;ATG4 autophagy related 4 homolog A;AUTL2;AUT-like 2 cysteine endopeptidase;AUT-like 2; cysteine endopeptidase;autophagin 2;Autophagin-2;autophagy-related cysteine endopeptidase 2;autophagy-related protein 4 homolog A;cysteine protease ATG4A;hAPG4A.
- Clonality:
- Polyclonal
- Extra Details:
- Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes; which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.
- Gene Details:
- autophagy related 4A cysteine peptidase
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human ATG4A.
- Molecular Weight:
- 45 kDa
- Protein Details:
- Cysteine protease ATG4A
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
