AOX1 Antibody
Product Sizes
100 ug
£496.00
OAAF03253-100UG
About this Product
- SKU:
- OAAF03253
- Additional Names:
- aldehyde oxidase;Aldehyde oxidase 1;AO;AOH1;azaheterocycle hydroxylase.
- Clonality:
- Polyclonal
- Extra Details:
- Oxidase with broad substrate specificity; oxidizing aromatic azaheterocycles; such as N1-methylnicotinamide; N-methylphthalazinium and phthalazine; as well as aldehydes; such as benzaldehyde; retinal; pyridoxal; and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir; catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir; which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis.
- Gene Details:
- aldehyde oxidase 1
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human AOX1.
- Molecular Weight:
- 147 kDa
- Protein Details:
- Aldehyde oxidase
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
