PARP3 Antibody
Product Sizes
100 ug
£496.00
OAAF03060-100UG
About this Product
- SKU:
- OAAF03060
- Additional Names:
- ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 2;ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 3;ADP-ribosyltransferase diphtheria toxin-like 3;ADPRT3;ADPRT-3;ADPRTL2;ADPRTL3;ARTD3;DNA ADP-ribosyltransferase PARP3;IRT1;NAD(+) ADP-ribosyltransferase 3;NAD+ ADP-ribosyltransferase 3;PADPRT-3;poly [ADP-ribose] polymerase 3;poly(ADP-ribose) synthetase-3;poly[ADP-ribose] synthase 3;poly[ADP-ribose] synthetase 3;protein mono-ADP-ribosyltransferase PARP3.
- Clonality:
- Polyclonal
- Extra Details:
- Involved in the base excision repair (BER) pathway; by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
- Gene Details:
- poly(ADP-ribose) polymerase family member 3
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human PARP3.
- Molecular Weight:
- 60 kDa
- Protein Details:
- Poly [ADP-ribose] polymerase 3
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
