BAX Antibody
Product Sizes
100 ug
£496.00
OAAF03001-100UG
About this Product
- SKU:
- OAAF03001
- Additional Names:
- apoptosis regulator BAX;Baxdelta2G9;Baxdelta2G9omega;Baxdelta2omega;BCL2 associated X protein;BCL2-associated X protein omega;bcl2-L-4;BCL2L4;bcl-2-like protein 4.
- Clonality:
- Polyclonal
- Extra Details:
- Plays a role in the mitochondrial apoptotic process. Under normal conditions; BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL; which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM) (PubMed:21458670). Under stress conditions; undergoes a conformation change that causes translocation to the mitochondrion membrane; leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3; and thereby apoptosis.
- Gene Details:
- BCL2 associated X; apoptosis regulator
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human BAX.
- Molecular Weight:
- 15 kDa
- Protein Details:
- Apoptosis regulator BAX
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
