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Antibodies

BCOR Antibody

Product Sizes
100 ug
£496.00
OAAF02835-100UG
About this Product
SKU:
OAAF02835
Additional Names:
ANOP2;BCL-6 coreceptor;BCL-6 corepressor;BCL6 interacting corepressor;BCL-6 interacting corepressor;MAA2;MCOPS2.
Clonality:
Polyclonal
Extra Details:
Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).
Gene Details:
BCL6 corepressor
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human BCOR.
Molecular Weight:
192 kDa
Protein Details:
BCL-6 corepressor
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody