MRC2 Antibody
Product Sizes
100 ug
£496.00
OAAF02717-100UG
About this Product
- SKU:
- OAAF02717
- Additional Names:
- CD280;CLEC13E;C-type lectin domain family 13 member E;C-type mannose receptor 2;ENDO180;endocytic receptor (macrophage mannose receptor family);endocytic receptor 180;macrophage mannose receptor 2;UPARAP;UPAR-associated protein;urokinase-type plasminogen activator receptor-associated protein.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU; and thus may regulate protease activity at the cell surface. May contribute to cellular uptake; remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
- Gene Details:
- mannose receptor C type 2
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human MRC2.
- Isotype:
- IgG
- Molecular Weight:
- 166 kDa
- Protein Details:
- C-type mannose receptor 2
- Purification:
- The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
