DYRK1A Antibody
Product Sizes
100 ug
£496.00
OAAF02420-100UG
About this Product
- SKU:
- OAAF02420
- Additional Names:
- dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A;dual specificity tyrosine-phosphorylation-regulated kinase 1A;dual specificity YAK1-related kinase;DYRK;DYRK1;HP86;MNB;mnb protein kinase homolog hp86;MNB/DYRK protein kinase;MNBH;MRD7;protein kinase minibrain homolog;serine/threonine kinase MNB;serine/threonine-specific protein kinase.
- Clonality:
- Polyclonal
- Extra Details:
- Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Modulates alternative splicing by phosphorylating the splice factor SRSF6 (By similarity). Exhibits a substrate preference for proline at position P+1 and arginine at position P-3. Has pro-survival function and negatively regulates the apoptotic process. Promotes cell survival upon genotoxic stress through phosphorylation of SIRT1. This in turn inhibits TP53 activity and apoptosis (By similarity).
- Gene Details:
- dual specificity tyrosine phosphorylation regulated kinase 1A
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human DYR1A.
- Molecular Weight:
- 85 kDa
- Protein Details:
- Dual specificity tyrosine-phosphorylation-regulated kinase 1A
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
