KLF11 Antibody
Product Sizes
100 ug
£496.00
OAAF02396-100UG
About this Product
- SKU:
- OAAF02396
- Additional Names:
- early growth response-alpha;EGRA;EGR-alpha;FKLF;FKLF1;Krueppel-like factor 10;Krueppel-like factor 11;MODY7;TGFB-inducible early growth response protein 1;TGFB-inducible early growth response protein 2;TIEG;TIEG1;TIEG2;TIEG-2;Tieg3;transforming growth factor-beta-inducible early growth response protein 1;transforming growth factor-beta-inducible early growth response protein 2;zinc finger transcription factor TIEG.
- Clonality:
- Polyclonal
- Extra Details:
- Transcription factor (PubMed:9748269; PubMed:10207080). Activates the epsilon- and gamma-globin gene promoters and; to a much lower degree; the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth (PubMed:9748269; PubMed:10207080; PubMed:16131492). Represses transcription of SMAD7 which enhances TGF-beta signaling (By similarity). Induces apoptosis (By similarity).|Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis; gluconeogenesis; and glycolysis in the liver. Represses the expression of PCK2; a rate-limiting step enzyme of gluconeogenesis (By similarity). May play a role in the cell cycle regulation.
- Gene Details:
- Kruppel like factor 10|Kruppel like factor 11
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human KLF10/11.
- Molecular Weight:
- 52 kDa
- Protein Details:
- Krueppel-like factor 10|Krueppel-like factor 11
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
