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Antibodies

MLLT10 Antibody

Product Sizes
100 ug
£496.00
OAAF02321-100UG
About this Product
SKU:
OAAF02321
Additional Names:
AF10;ALL1-fused gene from chromosome 10 protein;myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog; Drosophila); translocated to; 10;myeloid/lymphoid or mixed-lineage leukemia; translocated to; 10;protein AF-10;type I AF10 protein;type III AF10 protein;type IV AF10 protein.
Clonality:
Polyclonal
Extra Details:
Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells; binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation (PubMed:26439302).
Gene Details:
MLLT10 histone lysine methyltransferase DOT1L cofactor
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human AF10.
Molecular Weight:
109 kDa
Protein Details:
Protein AF-10
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody