UBA52 Antibody
Product Sizes
100 ug
£496.00
OAAF01979-100UG
About this Product
- SKU:
- OAAF01979
- Additional Names:
- 40S ribosomal protein S27a;CEP52;CEP80;epididymis luminal protein 112;epididymis secretory protein Li 50;HEL112;HEL-S-50;HMG20;HUBCEP52;L40;polyubiquitin B;polyubiquitin-B;polyubiquitin-C;RPL40;S27A;UBA80;UBC;UBCEP1;UBCEP80;Ubiquitin A-52 residue ribosomal protein fusion product 1;ubiquitin and ribosomal protein S27a;ubiquitin C;ubiquitin carboxyl extension protein 52;ubiquitin carboxyl extension protein 80;ubiquitin-40S ribosomal protein S27a;ubiquitin-52 amino acid fusion protein;ubiquitin-60S ribosomal protein L40;ubiquitin-CEP52;ubiquitin-CEP80.
- Clonality:
- Polyclonal
- Extra Details:
- Ubiquitin: Exists either covalently attached to another protein; or free (unanchored). When covalently bound; it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin); a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains; when attached to a target protein; have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis; DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins; however; in rare cases; conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin); it also has distinct roles; such as in activation of protein kinases; and in signaling.
- Gene Details:
- ribosomal protein S27a|ubiquitin A-52 residue ribosomal protein fusion product 1|ubiquitin B|ubiquitin C
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Ubiquitin.
- Molecular Weight:
- 8 kDa
- Protein Details:
- Polyubiquitin-B|Polyubiquitin-C|Ubiquitin-40S ribosomal protein S27a|Ubiquitin-60S ribosomal protein L40
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
