PIAS4 Antibody
Product Sizes
100 ug
£496.00
OAAF01959-100UG
About this Product
- SKU:
- OAAF01959
- Additional Names:
- E3 SUMO-protein ligase PIAS4;Piasg;PIAS-gamma;PIASY;protein inhibitor of activated STAT protein 4;protein inhibitor of activated STAT protein gamma;protein inhibitor of activated STAT protein PIASy;RING-type E3 ubiquitin transferase PIAS4;zinc finger; MIZ-type containing 6;ZMIZ6.
- Clonality:
- Polyclonal
- Extra Details:
- Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase; stabilizing the interaction between UBE2I and the substrate; and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways; including the STAT pathway; the p53/TP53 pathway; the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Mediates sumoylation of CEBPA; PARK7; HERC2; MYB; TCF4 and RNF168. In Wnt signaling; represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.
- Gene Details:
- protein inhibitor of activated STAT 4
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human PIAS4.
- Molecular Weight:
- 56 kDa
- Protein Details:
- E3 SUMO-protein ligase PIAS4
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
