Sodium Channel-pan Antibody
Product Sizes
100 ug
£496.00
OAAF01925-100UG
About this Product
- SKU:
- OAAF01925
- Additional Names:
- BFIC3;BFIS3;BFIS5;BFNIS;brain III voltage-gated sodium channel;cardiac tetrodotoxin-insensitive voltage-dependent sodium channel alpha subunit;CDCD2;CERIII;CIAT;CMD1E;CMPD2;CMS16;CTC-264K15.6;DEE11;DEE13;DEE6;DEE62;DEE6A;DEE6B;DRVT;EA9;EIEE11;EIEE13;EIEE6;EIEE62;ETHA;FEB3;FEB3A;FEB3B;FEPS2;FEPS3;FFEVF4;FHM3;GEFSP2;GEFSP7;HB1;HB2;HBA;HBBD;HBSC II;HBSCI;HBSCII;HH1;hNa6/Scn8a voltage-gated sodium channel;hNaN;hNE-Na;HOKPP2;HSAN2D;HSAN7;HYKPP;HYPP;ICCD;IVF;LQT3;MED;MYOCL2;Na(v)1.2;Na(V)1.4;NAC1;NAC1A;NAC2;NAC3;NaCh6;NaN;Nav1.1;Nav1.2;Nav1.3;Nav1.4;Nav1.5;Nav1.6;Nav1.7;Nav1.8;NAV1.9;NENA;NE-NA;neuroendocrine sodium channel;peripheral nerve sodium channel 3;peripheral nerve sodium channel 5;peripheral sodium channel 1;PFHB1;PN1;PN3;PN4;PN5;SCN1;SCN12A;SCN2A1;SCN2A2;sensory neuron sodium channel;sensory neuron sodium channel 2;SFNP;skeletal muscle sodium channel alpha subunit;skeletal muscle voltage-dependent sodium channel type IV alpha subunit;SkM1;SMEI;SNS;SNS-2;Sodium channel protein brain I subunit alpha;sodium channel protein brain II subunit alpha;sodium channel protein brain III subunit alpha;sodium channel protein cardiac muscle subunit alpha;sodium channel protein skeletal muscle subunit alpha;sodium channel protein type 1 subunit alpha;sodium channel protein type 10 subunit alpha;sodium channel protein type 11 subunit alpha;sodium channel protein type 2 subunit alpha;sodium channel protein type 3 subunit alpha;sodium channel protein type 4 subunit alpha;sodium channel protein type 5 subunit alpha;sodium channel protein type 8 subunit alpha;sodium channel protein type 9 subunit alpha;sodium channel protein type I subunit alpha;sodium channel protein type II subunit alpha;sodium channel protein type III subunit alpha;sodium channel protein type IV subunit alpha;sodium channel protein type IX subunit alpha;Sodium channel protein type V subunit alpha;Sodium channel protein type VIII subunit alpha;sodium channel protein type X subunit alpha;sodium channel protein type XI subunit alpha;sodium channel protein; brain I alpha subunit;sodium channel protein; brain type 2 alpha subunit;sodium channel voltage gated type 1 alpha subunit;sodium channel; voltage gated; type III alpha subunit;sodium channel; voltage gated; type VIII; alpha subunit;sodium channel; voltage-gated; type I; alpha polypeptide;sodium channel; voltage-gated; type I; alpha subunit;sodium channel; voltage-gated; type II; alpha 1 polypeptide;sodium channel; voltage-gated; type II; alpha 2 polypeptide;sodium channel; voltage-gated; type II; alpha subunit;sodium channel; voltage-gated; type III; alpha polypeptide;sodium channel; voltage-gated; type IV; alpha subunit;sodium channel; voltage-gated; type IX; alpha polypeptide;sodium channel; voltage-gated; type IX; alpha subunit;sodium channel; voltage-gated; type V; alpha subunit;sodium channel; voltage-gated; type X; alpha polypeptide;sodium channel; voltage-gated; type X; alpha subunit;sodium channel; voltage-gated; type XI; alpha polypeptide;sodium channel; voltage-gated; type XI; alpha subunit;sodium channel; voltage-gated; type XII; alpha polypeptide;SSS1;VF1;voltage-gated sodium channel alpha subunit Nav1.7;voltage-gated sodium channel subtype II;voltage-gated sodium channel subtype III;voltage-gated sodium channel subunit alpha Nav1.1;voltage-gated sodium channel subunit alpha Nav1.2;voltage-gated sodium channel subunit alpha Nav1.3;voltage-gated sodium channel subunit alpha Nav1.4;voltage-gated sodium channel subunit alpha Nav1.5;voltage-gated sodium channel subunit alpha Nav1.6;voltage-gated sodium channel subunit alpha Nav1.7;voltage-gated sodium channel subunit alpha Nav1.8;voltage-gated sodium channel subunit alpha Nav1.9;voltage-gated sodium channel type II alpha subunit;voltage-gated sodium channel type VIII alpha protein.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane; the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient (PubMed:7720699; PubMed:17167479; PubMed:25240195; PubMed:26680203; PubMed:15385606; PubMed:16988069; PubMed:17145499; PubMed:19369487; PubMed:24311784). It is a tetrodotoxin-sensitive Na(+) channel isoform (PubMed:7720699). Plays a role in pain mechanisms; especially in the development of inflammatory pain (PubMed:17167479; PubMed:17145499; PubMed:19369487; PubMed:24311784).|Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane; the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.|Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane; the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells; isoform 5 may participate in the control of podosome and invadopodia formation.|Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane; the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. Plays a key role in brain; probably by regulating the moment when neurotransmitters are released in neurons. Involved in sensory perception of mechanical pain: activation in somatosensory neurons induces pain without neurogenic inflammation and produces hypersensitivity to mechanical; but not thermal stimuli.|Tetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane; the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Plays a role in neuropathic pain mechanisms.|This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane; the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient (PubMed:1309946; PubMed:21447824; PubMed:25370050; PubMed:23420830; PubMed:23085483; PubMed:26279430; PubMed:26392562; PubMed:26776555). It is a tetrodotoxin-resistant Na(+) channel isoform (PubMed:1309946). This channel is responsible for the initial upstroke of the action potential. Channel inactivation is regulated by intracellular calcium levels (PubMed:19074138).|This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane; the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle.|This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane; the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Also involved; with the contribution of the receptor tyrosine kinase NTRK2; in rapid BDNF-evoked neuronal depolarization.
- Gene Details:
- sodium voltage-gated channel alpha subunit 1|sodium voltage-gated channel alpha subunit 10|sodium voltage-gated channel alpha subunit 11|sodium voltage-gated channel alpha subunit 2
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Sodium Channel.
- Isotype:
- IgG
- Molecular Weight:
- 227 kDa
- Protein Details:
- Sodium channel protein type 1 subunit alpha|Sodium channel protein type 10 subunit alpha|Sodium channel protein type 11 subunit alpha|Sodium channel protein type 2 subunit alpha|Sodium channel protein
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
