GZMB Antibody
Product Sizes
100 ug
£496.00
OAAF01817-100UG
About this Product
- SKU:
- OAAF01817
- Additional Names:
- C11;cathepsin G-like 1;Cathepsin G-like 2;cathepsin G-like 2; protein h-CCPX;CCPI;CCP-X;CGL1;CGL-1;CGL-2;CSPB;CSP-B;CSP-C;CTLA1;CTLA-1;CTSGL1;CTSGL2;cytotoxic serine protease B;Cytotoxic serine protease C;cytotoxic T-lymphocyte proteinase;cytotoxic T-lymphocyte proteinase 2;cytotoxic T-lymphocyte-associated serine esterase 1;cytotoxin serine protease-C;fragmentin 2;Fragmentin-2;granzyme B;granzyme B (granzyme 2; cytotoxic T-lymphocyte-associated serine esterase 1);granzyme H;Granzyme-2;HLP;human lymphocyte protein;SECT;T-cell serine protease 1-3E.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication.|This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3; -7; -9 and 10 to give rise to active enzymes mediating apoptosis.
- Gene Details:
- granzyme B|granzyme H
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Granzyme B.
- Isotype:
- IgG
- Molecular Weight:
- 27 kDa
- Protein Details:
- Granzyme B|Granzyme H
- Purification:
- The antibody was purified from rabbit antiserum by affinity chromatography using immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
