PTGS2 Antibody
Product Sizes
100 ug
£496.00
OAAF01763-100UG
About this Product
- SKU:
- OAAF01763
- Additional Names:
- COX2;COX-2;cyclooxygenase 2;cyclooxygenase 2b;Cyclooxygenase-2;GRIPGHS;hCox-2;PGG/HS;PGH synthase 2;PGHS-2;PHS II;PHS-2;prostaglandin G/H synthase 2;prostaglandin H2 synthase 2;Prostaglandin-endoperoxide synthase 2;prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase).
- Clonality:
- Polyclonal
- Extra Details:
- Converts arachidonate to prostaglandin H2 (PGH2); a committed step in prostanoid synthesis (PubMed:26859324; PubMed:27226593). Constitutively expressed in some tissues in physiological conditions; such as the endothelium; kidney and brain; and in pathological conditions; such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion; phenotypic changes; resistance to apoptosis and tumor angiogenesis. In cancer cells; PTGS2 is a key step in the production of prostaglandin E2 (PGE2); which plays important roles in modulating motility; proliferation and resistance to apoptosis.
- Gene Details:
- prostaglandin-endoperoxide synthase 2
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Cox2.
- Molecular Weight:
- 68 kDa
- Protein Details:
- Prostaglandin G/H synthase 2
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
