CDKN1B Antibody
Product Sizes
100 ug
£496.00
OAAF01395-100UG
About this Product
- SKU:
- OAAF01395
- Additional Names:
- CDKN4;cyclin-dependent kinase inhibitor 1B;cyclin-dependent kinase inhibitor 1B (p27; Kip1);Cyclin-dependent kinase inhibitor p27;KIP1;MEN1B;MEN4;P27KIP1.
- Clonality:
- Polyclonal
- Extra Details:
- Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A; but has little inhibitory activity on CDK2 bound to SPDYA (PubMed:28666995). Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly; stability; and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
- Gene Details:
- cyclin dependent kinase inhibitor 1B
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human p27 Kip1.
- Isotype:
- IgG
- Molecular Weight:
- 22 kda
- Protein Details:
- Cyclin-dependent kinase inhibitor 1B
- Purification:
- The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
