ESR2 Antibody
Product Sizes
100 ug
£496.00
OAAF01041-100UG
About this Product
- SKU:
- OAAF01041
- Additional Names:
- Erb;ER-BETA;ESRB;ESR-BETA;ESTRB;estrogen receptor beta;estrogen receptor beta 4;estrogen receptor beta splice variant; ERbeta2delta7;estrogen receptor beta splice variant; ERbeta4delta7;estrogen receptor beta splice variant; ERbeta6;estrogen receptor beta splice variant; ERbeta6delta7;estrogen receptor beta splice variant; ERbeta7;estrogen receptor beta splice variant; ERbeta7delta7;estrogen receptor beta splice variant; ERbetaEx. 4L;estrogen receptor beta splice variant; ERbetaEx. 6L;NR3A2;nuclear receptor subfamily 3 group A member 2;ODG8;oestrogen receptor beta.
- Clonality:
- Polyclonal
- Extra Details:
- Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1; and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner (PubMed:20074560). Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
- Gene Details:
- estrogen receptor 2
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Estrogen Receptor-beta.
- Molecular Weight:
- 59 kDa
- Protein Details:
- Estrogen receptor beta
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
