EIF4EBP1 Antibody
Product Sizes
100 ug
£496.00
OAAF01015-100UG
About this Product
- SKU:
- OAAF01015
- Additional Names:
- 4EBP1;4E-BP1;BP-1;eIF4E-binding protein 1;eukaryotic translation initiation factor 4E-binding protein 1;PHAS-I;phosphorylated heat- and acid-stable protein regulated by insulin 1.
- Clonality:
- Polyclonal
- Extra Details:
- Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E; leading to repress translation. In contrast; hyperphosphorylated form dissociates from EIF4E; allowing interaction between EIF4G1/EIF4G3 and EIF4E; leading to initiation of translation. Mediates the regulation of protein translation by hormones; growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
- Gene Details:
- eukaryotic translation initiation factor 4E binding protein 1
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human 4E-BP1.
- Molecular Weight:
- 12 kDa
- Protein Details:
- Eukaryotic translation initiation factor 4E-binding protein 1
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
